A Rare Case of Pseudoglucagonoma Syndrome Masquerading as Necrolytic Migratory Erythema

Contrast-enhanced computed tomography (CECT) abdomen showed atrophic pancreatic parenchyma with multiple intraparenchymal and ductal calcification; the largest calculus measuring 36x14 mm in the pancreatic head within the duct, dilated main pancreatic duct with side branches (maximum diameter 8.7 mm) with no obvious surrounding fat stranding, collection, postcontrast enhancement or focal lesions (Fig 2). NME associated with glucagonomas has a rapid rash resolution following surgical resection of the tumor.Pseudoglucagonoma syndrome has a protracted course as the underlying factors, such as pancreatitis, are almost irreversible, and treatment should be directed toward the underlying condition.As malnutrition seems common in pseudoglucagonoma syndrome, nutritional repletion with zinc, amino acids, and essential fatty acids can be considered. [...]our case raises the necessity of a thorough understanding of the course of illness with evaluation of different systems involved for the identification of pathology and for delineating the underlying etiology- pancreatitis and liver and GI disorders apart from glucagonoma in cases of NME.