The History and Applications of Phage Therapy in Pseudomonas aeruginosa

The History and Applications of Phage Therapy in Pseudomonas aeruginosa

The Pseudomonas aeruginosa is one of the bacteria that cause serious infections due to resistance to many antibiotics can be fatal in severe cases. Antimicrobial resistance is a global public health concern. To solve this problem, interest in phage therapy has revived; some studies are being develop...

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Veröffentlicht in:Microbiology research 2022-03, Vol.13 (1), p.14-37
Hauptverfasser: Silva, Carina, Sá, Sara, Guedes, Carla, Oliveira, Carla, Lima, Cláudio, Oliveira, Marco, Mendes, João, Novais, Gonçalo, Baylina, Pilar, Fernandes, Ruben
Format: Artikel
Sprache:eng
Schlagworte:
antibiotic
Antibiotics
Antimicrobial agents
Antimicrobial resistance
Bacteria
bacteriophages
Biofilms
Cystic fibrosis
Drug resistance
Enzymes
Gene expression
Genomes
Permeability
Phages
Plasmids
Pseudomonas aeruginosa
Public health
resistance
Therapy
Virulence
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Zusammenfassung:The Pseudomonas aeruginosa is one of the bacteria that cause serious infections due to resistance to many antibiotics can be fatal in severe cases. Antimicrobial resistance is a global public health concern. To solve this problem, interest in phage therapy has revived; some studies are being developed to try to prove the effectiveness of this therapy. Thus, in this opinion article, several historical aspects are addressed as well some applications of phage therapy against P. aeruginosa.
ISSN:2036-7481
2036-7481
DOI:10.3390/microbiolres13010002