Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV-specific neut...

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Veröffentlicht in:	Emerging infectious diseases 2021-05, Vol.27 (5), p.1472-1476
Hauptverfasser:	Alshukairi, Abeer N, Zhao, Jincun, Al-Mozaini, Maha A, Wang, Yanqun, Dada, Ashraf, Baharoon, Salim A, Alfaraj, Sara, Ahmed, Waleed A, Enani, Mushira A, Elzein, Fatehi E, Eltayeb, Nazik, Layqah, Laila, El-Saed, Aiman, Bahaudden, Husam A, Haseeb, Abdul, El-Kafrawy, Sherif A, Hassan, Ahmed M, Siddiq, Najlaa A, Alsharif, Ibtihaj, Qushmaq, Isamel, Azhar, Esam I, Perlman, Stanley, Memish, Ziad A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antibody Formation Asymptomatic Camelus Coronavirus Infections - epidemiology Coronaviruses Disease transmission Dispatch Epidemics Health aspects Humans Immune response Infections Intubation Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia MERS MERS-CoV Middle East respiratory syndrome Middle East Respiratory Syndrome Coronavirus Patients Pneumonia Respiratory diseases Saudi Arabia - epidemiology Severe acute respiratory syndrome coronavirus 2 Ventilators Viral antibodies viruses
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Beschreibung
Zusammenfassung:	Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV-specific neutralizing antibodies were detected for 6 years postinfection.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2705.204056