Relationship Between Driving Pressure During the First 24 Hours and Mortality Among Pediatric Critical Care Patients

Objective: Respiratory failure is one of the most common causes of mortality in pediatric intensive care unit (PICU) patients. Adult and a small number of pediatric studies have also associated driving pressure with mortality in ARDS patients, but studies showing the relationship between driving pressure and mortality in patients without ARDS are inconsistent and limited. This study aimed to determine whether driving pressure was associated with mortality in pediatric patients diagnosed as pediatric ARDS (pARDS) and non-pARDS who received mechanical ventilation support due to respiratory failure. Materials and Methods: Mechanically ventilated patients were recorded if the foreseen ventilation duration was more than 24 hours. Driving pressure and other ventilator parameters of patients in the pARDS and non-pARDS groups were compared with their 30-day mortality. Results: A total of 116 children were included in our study. 34 patients were classified in pARDS group, whereas 82 patients werein non-PARDS group. All patients’first day of mechanical ventilation parameters [ΔP (p