Effect of overweight/obesity and metabolic syndrome on frailty in middle‐aged and older Japanese adults

Background The potential for developing frailty exists in middle‐aged and older adults. While obesity and metabolic syndrome (MetS) increase the risk of frailty in older adults, this relationship remains unclear in middle‐aged adults, who are prone to developing lifestyle‐related diseases. Objective...

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Veröffentlicht in:	Obesity science & practice 2024-02, Vol.10 (1), p.e714-n/a
Hauptverfasser:	Nishida, Yuki, Yamada, Yosuke, Sasaki, Satoshi, Kanda, Eiichiro, Kanno, Yoshihiko, Anzai, Tatsuhiko, Takahashi, Kunihiko, Yamauchi, Keita, Katsukawa, Fuminori
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living Antidiabetics Antihypertensives Blood pressure Body mass index Body weight Body weight loss Codes Diabetes Diabetes mellitus Disease Drug dosages Dyslipidemia Frailty Glucose Health insurance Hospitals Hypertension Long term health care Longitudinal studies Metabolic disorders Metabolic syndrome Middle age Mortality Obesity Older people Original Overweight Population Risk factors Weight control
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Zusammenfassung:	Background The potential for developing frailty exists in middle‐aged and older adults. While obesity and metabolic syndrome (MetS) increase the risk of frailty in older adults, this relationship remains unclear in middle‐aged adults, who are prone to developing lifestyle‐related diseases. Objective To examine the effect of overweight/obesity and MetS on frailty development in middle‐aged and older Japanese adults using real‐world data. Methods This nationwide cohort study used exhaustive health insurance claims data of 3,958,708 Japanese people from 2015 to 2019 provided by the Japan Health Insurance Association. Participants aged ≥35 and
ISSN:	2055-2238 2055-2238
DOI:	10.1002/osp4.714