The insulin-sensitive side of SHIP2

A substantial and increasing proportion of death and disability in the EU (and elsewhere) is attributable to diseases associated with insulin resistance (i.e., decreased insulin sensitivity). Beside type II diabetes, other diseases like obesity, hypertension, atherosclerosis, hyperlipidaemia, polycy...

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Veröffentlicht in:	TheScientificWorld 2001, Vol.1, p.209-210
1. Verfasser:	Schurmans, S
Format:	Artikel
Sprache:	eng
Schlagworte:	5-phosphatase Animals Biochemistry, biophysics & molecular biology Biochimie, biophysique & biologie moléculaire Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - physiopathology Directions in Science Genetics & genetic processes Génétique & processus génétiques Humans insulin Insulin - pharmacology Insulin - physiology Insulin Resistance - genetics Insulin Resistance - physiology knock-out mice Life sciences lipid phosphatase Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases Phosphoric Monoester Hydrolases - genetics Phosphoric Monoester Hydrolases - metabolism Sciences du vivant SHIP2 type II diabetes mellitus
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Beschreibung
Zusammenfassung:	A substantial and increasing proportion of death and disability in the EU (and elsewhere) is attributable to diseases associated with insulin resistance (i.e., decreased insulin sensitivity). Beside type II diabetes, other diseases like obesity, hypertension, atherosclerosis, hyperlipidaemia, polycystic ovarian syndrome, and acromegaly are indeed associated with insulin resistance.
ISSN:	1537-744X 2356-6140 1537-744X
DOI:	10.1100/tsw.2001.34