Detrimental impact of solar and geomagnetic activity on plasma B-complex vitamins in the VA normative aging study cohort

It has been hypothesized that ultraviolet (UV) radiation can lead to depletion of plasma folate and B 12 vitamin, but few studies have investigated effects of other parameters of solar and geomagnetic activity (SGA). We investigated the association between four SGA parameters—interplanetary magnetic field (IMF), sunspot number (SSN), K p index, and ground shortwave solar radiation (SWR)—and three plasma B-complex vitamins—folate, B 6 , and B 12 —in 910 participants from the Normative Aging Study (NAS) between 1998 and 2017. Mixed-effects regression models were used for 1- to 28-moving day averages of SGA exposure, adjusted for covariates. We compared the impact of SGA in individuals under higher and lower B-complex supplementation (> or