Characteristics of CD56-positive cells in guinea pig lung in the dynamics of experimental allergic inflammation

The aim of this work is to study morphometric characteristics and distribution of CD56-positive cells in guinea pig lung in the dynamics of experimental allergic inflammation. Materials and methods. We studied the distribution and quantitative changes of CD56-positive cells in guinea pig lung in the dynamics of experimental allergic inflammation using histological, histochemical, immunohistochemical, morphometric and statistical methods. Results. The number of CD56-positive cells increased in the dynamics of experimental ovalbumin-induced allergic inflammation. The increase in the mean number of CD56-positive cells was found in the early period of allergic inflammation (on the 30th day, experimental group II) by 64.5 % (P*/**