Diastolic Dysfunction With Preserved Ejection Fraction After the Fontan Procedure

Diastolic Dysfunction With Preserved Ejection Fraction After the Fontan Procedure

Background Heart failure phenotyping in single-ventricle Fontan patients is challenging, particularly in patients with normal ejection fraction (EF). The objective of this study was to identify Fontan patients with abnormal diastolic function, who are high risk for heart failure with preserved eject...

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Veröffentlicht in:Journal of the American Heart Association 2022-01, Vol.11 (2), p.e024095-e024095
Hauptverfasser: Chowdhury, Shahryar M, Graham, Eric M, Taylor, Carolyn L, Savage, Andrew, McHugh, Kimberly E, Gaydos, Stephanie, Nutting, Arni C, Zile, Michael R, Atz, Andrew M
Format: Artikel
Sprache:eng
Schlagworte:
Child
Cross-Sectional Studies
Diastole
diastolic function
Fontan
Fontan Procedure - adverse effects
Heart Failure
Humans
Original Research
single ventricle
Stroke Volume
Ventricular Function, Left
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Zusammenfassung:Background Heart failure phenotyping in single-ventricle Fontan patients is challenging, particularly in patients with normal ejection fraction (EF). The objective of this study was to identify Fontan patients with abnormal diastolic function, who are high risk for heart failure with preserved ejection fraction (HFpEF), and characterize their cardiac mechanics, exercise function, and functional health status. Methods and Results Data were obtained from the Pediatric Heart Network Fontan Cross-sectional Study database. EF was considered abnormal if
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.121.024095