Inflammatory Marker but Not Adipokine Predicts Mortality among Long-Term Hemodialysis Patients

chronic inflammation contributes significantly to the morbidity and mortality of chronic hemodialysis patients. A recent research has shown that adipokines were associated with inflammation in these patients. We aim to investigate whether biomarkers of inflammation, adipokines, and clinical features...

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Veröffentlicht in:Mediators of Inflammation 2007-01, Vol.2007 (2), p.54-58
Hauptverfasser: TSAI, Yu-Che, LEE, Chien-Te, HUANG, Tiao-Lai, CHENG, Ben-Chung, KUO, Chien-Chun, SU, Yih, NG, Hwee-Yeong, YANG, Chih-Chau, CHUANG, Fong-Rong, LIAO, Shang-Chih
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Sprache:eng
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Zusammenfassung:chronic inflammation contributes significantly to the morbidity and mortality of chronic hemodialysis patients. A recent research has shown that adipokines were associated with inflammation in these patients. We aim to investigate whether biomarkers of inflammation, adipokines, and clinical features can predict the outcome of hemodialysis patients. we enrolled 181 hemodialysis patients (men: 97, mean age: 56.3+/-13.6) and analyzed predictors of long-term outcomes. during the 3-year followup period, 41 patients died; the main causes of death were infection and cardiovascular disease. Elevated serum levels of hsCRP and albumin and advanced age were highly associated with death (all P
ISSN:0962-9351
1466-1861
DOI:10.1155/2007/19891