Significance of inflammation in the development of vascular wall stiffness

This review deals with arterial wall stiffness in rheumatic diseases. It shows a role of inflammation in the pathogenesis of increased vascular stiffness, considers its mechanisms at the level of altered cell components, the clinical signs of an inflammation-arterial stiffness association and the po...

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Veröffentlicht in:Nauchno-prakticheskai͡a︡ revmatologii͡a 2013-04, Vol.51 (2), p.159-162
Hauptverfasser: Noskov, S M, Zavodchikov, Andrei Aleksandrovich, Shirokova, K Yu, Krasivina, I G, Lavrukhina, A A
Format: Artikel
Sprache:eng ; rus
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Zusammenfassung:This review deals with arterial wall stiffness in rheumatic diseases. It shows a role of inflammation in the pathogenesis of increased vascular stiffness, considers its mechanisms at the level of altered cell components, the clinical signs of an inflammation-arterial stiffness association and the possibilities of its reduction, and a search for novel therapeutic strategies to diminish the stiffness of arterial vessels with antirheumatic drugs.
ISSN:1995-4484
1995-4492
DOI:10.14412/1995-4484-2013-644