Microwave-assisted efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

An efficient one-pot synthesis of N 2 -(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed t...

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Veröffentlicht in:Beilstein journal of organic chemistry 2020-07, Vol.16 (1), p.1706-1712
Hauptverfasser: Moustafa, Moustafa Sherief, Mekheimer, Ramadan Ahmed, Al-Mousawi, Saleh Mohammed, Abd-Elmonem, Mohamed, El-Zorba, Hesham, Hameed, Afaf Mohamed Abdel, Mohamed, Tahany Mahmoud, Sadek, Kamal Usef
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Sprache:eng
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Zusammenfassung:An efficient one-pot synthesis of N 2 -(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.
ISSN:1860-5397
1860-5397
DOI:10.3762/bjoc.16.142