BRCA1 (185delAG) Mutation among Egyptian Breast Cancer Female Patients

BRCA1 (185delAG) Mutation among Egyptian Breast Cancer Female Patients

This study was conducted to estimate the frequency of BRCA1 (185delAG) mutation among Egyptian female patients with breast cancer. Forty selected female patients with breast cancer, 80 of their female relatives and 10 healthy females as a control group were included in this study. Result: The age of...

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Veröffentlicht in:Journal of High Institute of Public Health 2008-06, Vol.38 (2), p.409-424
Hauptverfasser: Mahmoud, Noha, Moustafa, Amal, Mahrous, Hanan, El-Gezeery, Amina, Mahmoud, Hesham, Abd El-Menam, Nadia
Format: Artikel
Sprache:eng
Schlagworte:
brca1 (185delag)
breast cancer
egyptian female patients
mutation
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Zusammenfassung:This study was conducted to estimate the frequency of BRCA1 (185delAG) mutation among Egyptian female patients with breast cancer. Forty selected female patients with breast cancer, 80 of their female relatives and 10 healthy females as a control group were included in this study. Result: The age of onset of breast cancer was below 40 years in 25 (62.5%) patients and above 40 years in 15 (37.5%) patients. There were significant differences among the patients regarding the age at menarche before 13 years (p=0.011, p
ISSN:2357-061X
2357-0601
2357-061X
DOI:10.21608/jhiph.2008.20895