Enabling Cyclization Strategies through Carbonyl-Ylide-Mediated Synthesis of Malonate Enol Ethers

Enabling Cyclization Strategies through Carbonyl-Ylide-Mediated Synthesis of Malonate Enol Ethers

Malonate enol ethers are afforded in one step by condensation of cyclic ketones with α-diazomalonates under [CpRu(CH CN) ][BAr ] catalysis. The dual reactivity of these 2-vinyloxymalonates can be used to expand the classical range of cyclizations derived from carbonyl ylide intermediates.

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Veröffentlicht in:ACS Organic & Inorganic Au 2021-10, Vol.1 (1), p.11-17
Hauptverfasser: Viñas-Lóbez, Júlia, Levitre, Guillaume, de Aguirre, Adiran, Besnard, Céline, Poblador-Bahamonde, Amalia I, Lacour, Jérôme
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Sprache:eng
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Letter
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Zusammenfassung:Malonate enol ethers are afforded in one step by condensation of cyclic ketones with α-diazomalonates under [CpRu(CH CN) ][BAr ] catalysis. The dual reactivity of these 2-vinyloxymalonates can be used to expand the classical range of cyclizations derived from carbonyl ylide intermediates.
ISSN:2694-247X
2694-247X
DOI:10.1021/acsorginorgau.1c00006