Association between pre-pregnancy body mass index and gestational weight gain and the risk of preeclampsia: A systematic review and meta-analysis

Objective:To analyze the relationship between body mass index (BMI) before pregnancy and gestational weight gain throughout pregnancy with the incidence of preeclampsia. Methods:This was a systematic review-meta analysis of literature collected from three e-databases:Scopus, PubMed, and Science Direct. Quality assessment was measured with the Effective Public Health Practice Project methods. Meta-analysis was done by calculating the fixed and random-effects of odds ratio (OR) for each BMI category and gestational weight gain as compared with the incidence of preeclampsia. Results:Overweight was associated with a significantly increased risk of preeclampsia (OR=2.152, 95％ CI 1.363-3.400; P=0.001). Obesity was also associated with a noticeably increased risk of preeclampsia (OR=2.856, 95％ CI 1.755-4.649; P