Epidemiological surveillance of pancreatic cancer in the North region of the state of Rio Grande do Sul
Introduction: Pancreatic neoplasia is considered a serious disease, associated with high mortality rates and late diagnosis. This pathology corresponds in the Brazilian scenario, about 2% of the diagnosed cancers. The main risk factors are: advanced age, male sex, black race, smoking, obesity, diabe...
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Veröffentlicht in: | Brazilian Journal of Oncology 2020-01, Vol.16 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Introduction: Pancreatic neoplasia is considered a serious disease, associated with high mortality rates and late diagnosis. This pathology corresponds in the Brazilian scenario, about 2% of the diagnosed cancers. The main risk factors are: advanced age, male sex, black race, smoking, obesity, diabetes, pancreatitis, excessive alcohol use, as well as genetic syndromes such as non-polypoid hereditary colorectal cancer (HNPCC) and breast and ovary (associated with BRCA2 mutations). Objectives: The objective of this study was to identify the main risk factors and to verify which variables related to diagnosis, treatment and staging were present in cases of pancreatic cancer registered in the São Vicente de Paulo Hospital (HSVP) epidemiological surveillance system for cancer. Methods: A cross-sectional, predominantly descriptive, retrospective study using data from patients with pancreatic cancer at the Hospital São Vicente de Paulo (HSVP) was conducted between 2007 and 2017. Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS), version 18.0, (SPSS Inc., Chicago, IL, USA). Results: A higher incidence was observed in men (51.2%), the predominant age range was between 66 and 80 years (41.9%), the white color was prevalent (91.7%), (13,3%) were users of alcoholic beverages, (33.9%) were smokers or former smokers, (44.9%) were in stage IV when diagnosed and the predominant life span was between 1 and 10 months (35.7%). Conclusions: The risk factors recommended by the literature, with the exception of the black race, are present in the epidemiological profile traced by the present study. In addition, high mortality and late diagnosis were also evidenced through the stage during the diagnosis and the low survival rate. Thus, the study is relevant for the adoption of future preventive and diagnostic measures. |
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ISSN: | 2526-8732 |
DOI: | 10.5935/2526-8732.20200009 |