Suture trabeculotomy ab interno for secondary glaucoma in Japanese patients with Val30Met hereditary transthyretin amyloidosis

We retrospectively evaluated surgical outcomes of suture trabeculotomy (SLOT) ab interno for secondary glaucoma in 18 eyes of 12 patients with hereditary transthyretin (ATTRv) amyloidosis with Val30Met mutation. SLOT ab interno was performed between May 2015 and January 2020. All the participants we...

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Veröffentlicht in:	Scientific reports 2022-11, Vol.12 (1), p.19330-19330, Article 19330
Hauptverfasser:	Kawaji, Takahiro, Sato, Tomoki
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/3161 692/699/3161/3165 692/699/3161/3169/3170 Amyloid Neuropathies, Familial - complications Amyloid Neuropathies, Familial - genetics Amyloid Neuropathies, Familial - surgery Amyloidosis Eye Follow-Up Studies Glaucoma Glaucoma - complications Glaucoma - genetics Glaucoma - surgery Glaucoma, Open-Angle - complications Humanities and Social Sciences Humans Intraocular Pressure Japan multidisciplinary Patients Retrospective Studies Science Science (multidisciplinary) Survival Sutures Trabeculectomy - methods Transthyretin Treatment Outcome
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Zusammenfassung:	We retrospectively evaluated surgical outcomes of suture trabeculotomy (SLOT) ab interno for secondary glaucoma in 18 eyes of 12 patients with hereditary transthyretin (ATTRv) amyloidosis with Val30Met mutation. SLOT ab interno was performed between May 2015 and January 2020. All the participants were followed up for at least 12 months. The primary outcome measure was Kaplan–Meier survival. Failure of this treatment was defined as an intraocular pressure (IOP) of ≥ 22 mmHg and a
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-022-23150-8