Alkaloids and Phenolic Compounds from Sida rhombifolia L. (Malvaceae) and Vasorelaxant Activity of Two Indoquinoline Alkaloids

The follow-up of phytochemical and pharmacological studies of L. (Malvaceae) aims to strengthen the chemosystematics and pharmacology of genera and support the ethnopharmacological use of this species as hypotensive herb. The present work reports phytoconstituents isolated and identified from aerial...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2017-01, Vol.22 (1), p.94-94
Hauptverfasser: Chaves, Otemberg Souza, Teles, Yanna Carolina Ferreira, Monteiro, Matheus Morais de Oliveira, Mendes Junior, Leônidas das Graças, Agra, Maria de Fátima, Braga, Valdir de Andrade, Silva, Tânia Maria Sarmento, Souza, Maria de Fátima Vanderlei de
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Sprache:eng
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Zusammenfassung:The follow-up of phytochemical and pharmacological studies of L. (Malvaceae) aims to strengthen the chemosystematics and pharmacology of genera and support the ethnopharmacological use of this species as hypotensive herb. The present work reports phytoconstituents isolated and identified from aerial parts of by using chromatographic and spectroscopic methods. The study led to the isolation of scopoletin ( ), scoporone ( ), ethoxy-ferulate ( ), kaempferol ( ), kaempferol-3- -β-d-glycosyl-6''-α-d-rhamnose ( ), quindolinone ( ), 11-methoxy-quindoline ( ), quindoline ( ), and the cryptolepine salt ( ). The alkaloids quindolinone ( ) and cryptolepine salt ( ) showed vasorelaxant activity in rodent isolated mesenteric arteries.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules22010094