In vivo monitoring of hepatic glycolipid distribution of n -6 ∕ n -3 in jugular-vein-cannulated rats as a nutritional research model for monogastric animal

The metabolic distribution via blood from liver of glycerolipids by omega-6 to omega-3 fatty acid (n-6 ∕ n-3) ratio in monogastric animal nutrition is very important. In vivo monitoring technique using jugular-vein-cannulated rats as a nutritional model for monogastric animal can yield important insights into animal nutrition. This study was conducted to determine the effect of different n-6 ∕ n-3 ratios (71:1, 4:1, 15:1, 30:1) on metabolic distribution of glycerolipids newly synthesized and secreted in the liver of the rats and explore the mechanism involved. Regarding 14CO2 released from oxidation of glycerolipid metabolism, it was the highest (22.5 %) in groups with a n-6 ∕ n-3 ratio of 4:1 (P