Is there an increased risk of hip fracture in multiple sclerosis? Analysis of the Nationwide Inpatient Sample

Is there an increased risk of hip fracture in multiple sclerosis? Analysis of the Nationwide Inpatient Sample

Impaired ambulation, frequent falls, and prolonged immobilization combined with the high rate of vitamin D deficiency in people with multiple sclerosis (MS) could lead to an increased risk of hip fracture. A retrospective cohort analysis of 20 years of the Nationwide Inpatient Sample (AHRQ.gov), a 2...

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Veröffentlicht in:Journal of multidisciplinary healthcare 2014-01, Vol.7 (default), p.119-122
Hauptverfasser: Bhattacharya, Rajib K, Vaishnav, Niralee, Dubinsky, Richard M
Format: Artikel
Sprache:eng
Schlagworte:
Complications and side effects
Health risk assessment
Hip fractures
Mortality
Multiple sclerosis
Original Research
osteoporosis
patients at risk
Physiological aspects
Risk factors
Vitamin D deficiency
Vitamin deficiency
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Zusammenfassung:Impaired ambulation, frequent falls, and prolonged immobilization combined with the high rate of vitamin D deficiency in people with multiple sclerosis (MS) could lead to an increased risk of hip fracture. A retrospective cohort analysis of 20 years of the Nationwide Inpatient Sample (AHRQ.gov), a 20% stratified yearly sample of USA hospital admissions from the year 1988-2007, was performed. Based on International Classification of Diseases Ninth Revision (ICD9) codes, admissions with a primary diagnosis of acute hip fracture (ICD9 code 226.xx) and a secondary diagnosis of MS (ICD9 code 340) was identified. Indirect adjustment was used to compare the prevalence of MS in this population with that of the USA. Significance was set a priori at P
ISSN:1178-2390
1178-2390
DOI:10.2147/JMDH.S54786