Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

Three new heptelidic acid derivatives ( 1 – 3 ) including two new dimeric esters and two known heptelidic acid analogues ( 4 and 5 ) were isolated from the solid culture of mushroom Lentinellus ursinus . The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Natural Products and Bioprospecting 2018-10, Vol.8 (5), p.355-360
Hauptverfasser: Liu, Li, Han, Jun-Jie, Xu, Tian-Shun, Liu, Rui-Xing, Bao, Li, Liu, Hong-Wei
Format: Artikel
Sprache:eng
Schlagworte:
Antibacterial activity
Biomedical and Life Sciences
Bioorganic Chemistry
Biosynthetic pathway
Derivatives
E coli
Esters
Food Science
Heptelidic acid derivatives
Identification and classification
Lentinellus ursinus
Life Sciences
Medicinal Chemistry
Mushrooms
NMR
Nuclear magnetic resonance
Original
Original Article
Pharmacology/Toxicology
Physiological aspects
Plant Biochemistry
Plant Sciences
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Three new heptelidic acid derivatives ( 1 – 3 ) including two new dimeric esters and two known heptelidic acid analogues ( 4 and 5 ) were isolated from the solid culture of mushroom Lentinellus ursinus . The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1 – 5 was postulated. Compounds 1 – 5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. Graphical Abstract
ISSN:2192-2195
2192-2209
DOI:10.1007/s13659-018-0168-8