Calcified intracranial tuberculomas as sequelae of pediatric neurotuberculosis

A 29-year-old woman with a history of neurotuberculosis at the age of 18 months presented with seizures, abnormal gait, and fluctuations of consciousness level, recovering after anti-tuberculosis treatment. She remained asymptomatic for the next years, except for moderate cognitive impairment. Years later, a brain magnetic resonance imaging scan revealed calcified lobulated masses in the brain parenchyma and basal cisterns. Intracranial tuberculomas occur in 5%-24% of pediatric neurotuberculosis and can be secondary to pial vessel inflammation, perivascular abscesses, or septic emboli. Medical history and the characterization of non-enhancing, diffusely calcified brain masses are important clues for diagnosing residual granulomas.