Association of sleep duration and depressive symptoms with mortality in cancer survivors
Evidence of the association between sleep duration, depressive symptoms, and mortality in cancer survivors is limited. 2,111 participants from the National Health and Nutrition Examination Surveys were involved and linked to a mortality database up to 31 December 2019. Sleep duration was self-report...
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Veröffentlicht in: | BMC cancer 2024-12, Vol.24 (1), p.1573-10, Article 1573 |
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Sprache: | eng |
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Zusammenfassung: | Evidence of the association between sleep duration, depressive symptoms, and mortality in cancer survivors is limited.
2,111 participants from the National Health and Nutrition Examination Surveys were involved and linked to a mortality database up to 31 December 2019. Sleep duration was self-reported at baseline. Depressive symptom was assessed using the Patient Health Questionnaire (PHQ-9) and a total score of ≥ 10 is considered clinically relevant depressive symptoms. Cox proportional hazards regression model was the main statistical models.
A 2% increase in all-cause mortality was found for each 1-point increase in depressive symptoms score (hazard ratio [HR], 1.02; 95% confidence interval [CI], 1.00-1.03). Compared with those patients who slept 7 h, positive associations of 8 h (HR, 1.49; 95% CI, 1.09-2.05) durations with all-cause mortality were observed. In the joint analysis, cancer survivors with depressive symptoms had a higher risk of all-cause mortality when sleeping |
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ISSN: | 1471-2407 1471-2407 |
DOI: | 10.1186/s12885-024-13302-6 |