Disturbance In The Composition of Lipoprotein Particles And Chronic Inflammation As Prognostic Factors In The Development of Coronary Disease

The study focused on 30 dyslipidemic patients (12 women and 18 men); 16 of them had coronary disease (CD). The concentrations of apoA and apoB were determined in all patients, as well as the calculated ratio between apoA and apoB. As far as inflammatory indicators are concerned, the concentrations o...

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Veröffentlicht in:Journal of medical biochemistry 2007-01, Vol.26 (1), p.25-28
Hauptverfasser: Jovovic, Biljana, Lecc, Nevenka, Jelic, Marija, Damnjanovic, Goran, Dindic, Boris, Sokolovic, Dusan
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Sprache:eng
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Zusammenfassung:The study focused on 30 dyslipidemic patients (12 women and 18 men); 16 of them had coronary disease (CD). The concentrations of apoA and apoB were determined in all patients, as well as the calculated ratio between apoA and apoB. As far as inflammatory indicators are concerned, the concentrations of sensitive C reactive protein (hsCRP), albumin, fibrinogen, intracellular adhesive molecule (ICAM-1) and vascular adhesive molecule (VCAM -1) were determined. In patients with CD there were considerably higher concentrations of fibrinogen (3.1 ± 1.2 vs. 2.7 ± 0.7 g/L) and VCAM-1 (10.9 ± 3.6 vs. 8.3 ± 2.8 g/L) (p
ISSN:1452-8258
1452-8266
DOI:10.2478/v10011-007-0004-x