Pick the best of both glucose and lipid metabolism

Pick the best of both glucose and lipid metabolism

Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinic...

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Veröffentlicht in:Journal of Cutaneous Immunology and Allergy 2022-07, Vol.13 (7), p.1132-1133
Hauptverfasser: Shimizu, Tatsunori, Takahashi, Yuya, Fujita, Hiroki, Waki, Hironori
Format: Artikel
Sprache:eng
Schlagworte:
Adipocytes
Body fat
Commentaries
Dextrose
Diabetes
Glucose
Glucose metabolism
Insulin
Insulin resistance
Insulin-like growth factors
Kinases
Lipid metabolism
Lipogenesis
Liver
Liver diseases
Muscles
Musculoskeletal system
Phosphorylation
Protein biosynthesis
Protein kinases
Protein synthesis
Proteins
Sterols
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Zusammenfassung:Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinical benefits in the treatment of diabetes.
ISSN:2040-1116
2040-1124
DOI:10.1111/jdi.13774