EVALUATION OF PROGNOSTIC SIGNIFICANCE OF FUNCTIONAL AND BIOCHEMICAL INDICES FOR HEALTH STATUS ASSESSMENT IN YOUNG PERSONS WORKING IN TUBE-CASTING PLANTS

The authors analyzed the changes of functional and biochemical indices in young persons engaged in tube-casting plants and exposed to harmful physical and chemical factors. Some indices were deviated from their normal values 10–60 %. Signs of noise exposure to organs of hearing, disorders of hand-arm vibration sensitivity, retina angiopathy. Elevated IgE fraction, high oxidative stress, superoxidismutase activity reduction were revealed. The performed studies show a significance of functional and biochemical indices in young persons engaged in tube-casting plants since the indices reflect a development of preclinical pathologies which could lead to onset of occupational diseases in lack of proper preventive measures.