Diagnostic challenges of central nervous system tuberculosis

Central nervous system tuberculosis (TB) was identified in 20 cases of unexplained encephalitis referred to the California Encephalitis Project. Atypical features (encephalitic symptoms, rapid onset, age) and diagnostic challenges (insensitive cerebrospinal fluid [CSF] TB PCR result, elevated CSF gl...

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Veröffentlicht in:	Emerging infectious diseases 2008-09, Vol.14 (9), p.1473-1475
Hauptverfasser:	Christie, Laura J, Loeffler, Ann M, Honarmand, Somayeh, Flood, Jennifer M, Baxter, Roger, Jacobson, Susan, Alexander, Rick, Glaser, Carol A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antitubercular Agents - pharmacology California - epidemiology Central nervous system Child Child, Preschool Diagnosis Dispatch encephalitis Female Health aspects Humans Infant Male Medical tests meningitis Methods Middle Aged Mycobacterium Mycobacterium bovis Mycobacterium bovis - drug effects Mycobacterium bovis - isolation & purification Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - isolation & purification Risk factors Tuberculosis Tuberculosis, Central Nervous System - cerebrospinal fluid Tuberculosis, Central Nervous System - diagnosis Tuberculosis, Central Nervous System - epidemiology Tuberculosis, Central Nervous System - microbiology
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Beschreibung
Zusammenfassung:	Central nervous system tuberculosis (TB) was identified in 20 cases of unexplained encephalitis referred to the California Encephalitis Project. Atypical features (encephalitic symptoms, rapid onset, age) and diagnostic challenges (insensitive cerebrospinal fluid [CSF] TB PCR result, elevated CSF glucose levels in patients with diabetes, negative result for tuberculin skin test) complicated diagnosis.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1409.070264