Pulmonary dysfunction in overweight and obese children with obstructive sleep apnoea

Pulmonary dysfunction in overweight and obese children with obstructive sleep apnoea

Introduction Overweight and obese children are at risk of obstructive sleep apnoea (OSA) and abnormal pulmonary function (PF). Aim Investigate the relationship between body mass index (BMI), OSA on PF in children. Materials & Method Seventy‐four children were recruited. Mixed obstructive apnoea‐...

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Veröffentlicht in:Endocrinology, diabetes & metabolism diabetes & metabolism, 2023-05, Vol.6 (3), p.e417-n/a
Hauptverfasser: Kasim, Aina Salwa, Golbabapour, Shahram, Zaini, Azriyanti Anuar, Peng, Eg Kah, Jalaludin, Muhammad Yazid, Nathan, Anna Marie, Chinna, Karuthan, Thavagnanam, Surendran
Format: Artikel
Sprache:eng
Schlagworte:
Body Mass Index
Child
children
cytokines
Humans
Laboratories
Nitric oxide
Obesity
obstructive sleep apnoea
overweight
Overweight - complications
Pediatric Obesity - complications
pulmonary function
Respiratory Insufficiency
Sleep apnea
Sleep Apnea, Obstructive - complications
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Zusammenfassung:Introduction Overweight and obese children are at risk of obstructive sleep apnoea (OSA) and abnormal pulmonary function (PF). Aim Investigate the relationship between body mass index (BMI), OSA on PF in children. Materials & Method Seventy‐four children were recruited. Mixed obstructive apnoea‐hypopnea index (MOAHI), BMI, oxygen saturation (SpO2), forced expiratory volume one second (FEV1), forced vital capacity (FVC) and fractionated exhaled nitric oxide (FeNO) were measured. Results Twenty‐four and thirty children had mild OSA and moderate‐to‐severe OSA respectively. BMI correlated negatively with SpO2 nadir (r = −.363, p = .001). FVC, FEV1 and nadir SpO2 values decreased with OSA severity (p 
ISSN:2398-9238
2398-9238
DOI:10.1002/edm2.417