Study of the relationship between regional cerebral saturation and pCO2 changes during mechanical ventilation to evaluate modifications in cerebral perfusion in a newborn piglet model

Near-infrared spectroscopy (NIRS) could be a useful continuous, non-invasive technique for monitoring the effect of partial pressure of carbon dioxide (PaCO2) fluctuations in the cerebral circulation during ventilation. The aim of this study was to examine the efficacy of NIRS to detect acute change...

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Veröffentlicht in:	Brazilian journal of medical and biological research 2022, Vol.55, p.e11543-e11543
Hauptverfasser:	Silvera, F, Gagliardi, T, Vollono, P, Fernández, C, García-Bayce, A, Berardi, A, Badía, M, Beltrán, B, Cabral, T, Abella, P, Farías, L, Vaamonde, L, Martell, M, Blasina, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Autoregulation BIOLOGY Blood flow Blood glucose Blood pressure Carbon Dioxide Carbon dioxide pressure Cerebral blood flow Cerebrovascular Circulation - physiology Doppler effect Hemoglobin Hypercapnia Hyperventilation Hypocapnia Hypoventilation Infrared spectroscopy Jugular vein Mechanical ventilation MEDICINE, RESEARCH & EXPERIMENTAL Newborn NIRS Oxygen Oxygenation Respiration, Artificial Swine Ventilation
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Zusammenfassung:	Near-infrared spectroscopy (NIRS) could be a useful continuous, non-invasive technique for monitoring the effect of partial pressure of carbon dioxide (PaCO2) fluctuations in the cerebral circulation during ventilation. The aim of this study was to examine the efficacy of NIRS to detect acute changes in cerebral blood flow following PaCO2 fluctuations after confirming the autoregulation physiology in piglets. Fourteen piglets (
ISSN:	0100-879X 1414-431X 1414-431X 1678-4510
DOI:	10.1590/1414-431X2022e11543