Effect Of Pomegrante Peels And Bay Leaves On Multidrug Resistant Bacteria Isolated From Urinary Tract Infection Patients

Background: Alternative natural therapy by plants extracts had opened wide door for the use of natural products as an alternative therapy instead of many antibiotics and drugs , which had many harmful side effects.Also, an increased interest has been centered on the industrial wastes, especially plant raw materials which contain phenols (e.g. Pomegranate peel and Bay leaves) which is a sources of natural antioxidants ,which are on the contrary of synthetic antioxidants that had restrict use due to their health risks , carcinogenesis and toxicity . Objectives :This study was done to find out the etiology and sensitivity pattern of uropathogenic bacteria isolated from patients with urinary tract infection , in order to select the bacterial isolates that had multidrug resistance . Type of the study: Cross-sectional study. Methods: preparation of Hot water extract , Cold water extract , Methanol extract and Ethanol extract of both Pomegranate peels and Bay leaves and test there antibacterial activity against these uropathogenic bacteria which are multidrug resistant . Results :All extracts from pomegranate fruit peels exhibited inhibitory activity against all tested bacteria . Hot , Cold water extract and Ethanol extract of pomegranate peels recorded the highest inhibition zones compared with the Methanol extract. On the other hand, there were no antibacterial activity of any extract of Bay leaves on any of tested bacteria. The medicinal plants antibacterial activity was well documented and those plants are new potential alternative antibacterial agent especially against multi resistant bacteria which had been the center of focus globally. Conclusions: Pomegranate have antibacterial activity against multidrug resistant pathogenic bacteria isolated from UTI patients , So it emerged as alternative therapy for humans leading to reduction the cost and the risk of using antibiotics .