Modified Classical Graph Algorithms for the DNA Fragment Assembly Problem

DNA fragment assembly represents an important challenge to the development of efficient and practical algorithms due to the large number of elements to be assembled. In this study, we present some graph theoretical linear time algorithms to solve the problem. To achieve linear time complexity, a hea...

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Veröffentlicht in:Algorithms 2015-09, Vol.8 (3), p.754-773
Hauptverfasser: Mallen-Fullerton, Guillermo M, Quiroz-Ibarra, J Emilio, Miranda, Antonio, Fernandez-Anaya, Guillermo
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Sprache:eng
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Zusammenfassung:DNA fragment assembly represents an important challenge to the development of efficient and practical algorithms due to the large number of elements to be assembled. In this study, we present some graph theoretical linear time algorithms to solve the problem. To achieve linear time complexity, a heap with constant time operations was developed, for the special case where the edge weights are integers and do not depend on the problem size. The experiments presented show that modified classical graph theoretical algorithms can solve the DNA fragment assembly problem efficiently.
ISSN:1999-4893
1999-4893
DOI:10.3390/a8030754