FRACTURE RISK AND OBSTRUCTIVE SLEEP APNOEA

Obstructive Sleep Apnoea (OSA) with hypoxemia, oxidative stress, low-grade inflammation and multiple hormonal metabolic changes affect the bone metabolism. This leads to an increased fracture risk in patients with OSA. Purpose: The aim of the study was to explore the connection between fracture risk and newly-diagnosed OSA. Materials/methods: 130 patients with newly diagnosed OSA and 67 controls without OSA were included in the study. Anthropometric, laboratory, instrumental and study tests and fracture risk assessment under the FRAX program were performed. Results: There isn’t a statistical difference in the age and gender in the OSA group compared to the controls (p>0.05). A statistically significant difference between the OSA group and the control group was found with regard to the body mass index (BMI), visceral fat mass ratio (VFR), neck circumference, Epworth sleepiness scale (ESS), Vitamin D levels, beta-crosslaps and osteocalcin (р