Visceral Leishmaniasis: A Case Confirmed by Metagenomic Next-Generation Sequencing from Northwestern China

Visceral leishmaniasis (VL), also known as kala-azar. It is characterized by prolonged intermittent fever, anemia, splenomegaly, hepatomegaly, and skin darkening. VL is primarily endemic in regions, such as Brazil, East Africa, and India. However, Northern Xinjiang, which is located in northwestern...

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Veröffentlicht in:Infection and drug resistance 2024-07, Vol.17, p.3153-3158
Hauptverfasser: Li, Ente, Zhu, Qingfeng, Lv, Ziman, Xie, Songsong, Zhang, Chunju, Li, Wei, Mi, Ligu, Liu, Quan, Wang, Yuanzhi, Lu, Xiaobo
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Sprache:eng
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Zusammenfassung:Visceral leishmaniasis (VL), also known as kala-azar. It is characterized by prolonged intermittent fever, anemia, splenomegaly, hepatomegaly, and skin darkening. VL is primarily endemic in regions, such as Brazil, East Africa, and India. However, Northern Xinjiang, which is located in northwestern China, is considered a low-incidence area for VL, contributing to its status as a neglected infectious disease. In this report, we present a case of VL caused by that was diagnosed using metagenomic next-generation sequencing (mNGS). This case underscores the diagnostic value of mNGS, particularly in regions with low incidence of VL.
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S472172