DETERMINATION OF ACTIVITY OF INFLAMMATION IN INFECTIVE ENDOCARDITIS

DETERMINATION OF ACTIVITY OF INFLAMMATION IN INFECTIVE ENDOCARDITIS

Aim. Study of diagnostic significance of serum level of tumor necrotizing factor a (TNF-a), C-reactive protein (C-RP) and procalcitonin (PCT) in infective endocarditis (IE).Methods. 66 patients with IE (60,6% male, 39,4% female), 35 with primary IE, 31 - with secondary IE, were included into the stu...

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Veröffentlicht in:Sechenovskiĭ vestnik 2022-12 (2), p.28-33
Hauptverfasser: T. A. Fedorova, V. N. Yakovlev, N. A. Semenenko, S. Ya. Tazina, A. P. Roytman, M. K. Rybakova
Format: Artikel
Sprache:rus
Schlagworte:
c-reactive protein
diagnosis
infective endocarditis
procalcitonin
tumor necrosis factor a
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Zusammenfassung:Aim. Study of diagnostic significance of serum level of tumor necrotizing factor a (TNF-a), C-reactive protein (C-RP) and procalcitonin (PCT) in infective endocarditis (IE).Methods. 66 patients with IE (60,6% male, 39,4% female), 35 with primary IE, 31 - with secondary IE, were included into the study. Clinical and laboratory investigation included determination of serum concentration of TNF-a, C-RP and PCT.Results. Dynamics of serum concentration of TNF-a, C-RP and PCT were described, types of changes of this parameters, which showed an unfavorable prognosis of infective endocarditis, were distinguished.Conclusion. Determination of serum level of TNF-a, C-RP and PCT can be used for description of the disease severity.
ISSN:2218-7332
2658-3348