Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response

Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case of EGPA-related pancolitis and st...

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Veröffentlicht in:Case Reports in Gastroenterology 2023-01, Vol.17 (1), p.162-166
Hauptverfasser: Lai, Mark, He, Tony, Wright, Emily K.
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Asthma
Biopsy
Blood
Case reports
colitis
Colon
Conflicts of interest
eosinophilic granulomatous polyangiitis
Gastrointestinal diseases
Hay fever
Histopathology
Inflammatory diseases
Intestinal obstruction
Ischemia
mepolizumab
Monoclonal antibodies
Remission (Medicine)
Rhinitis
Single Case
Vein & artery diseases
Wegener's granulomatosis
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Zusammenfassung:Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case of EGPA-related pancolitis and stricturing small bowel disease managed with a combination of mepolizumab and surgical resection.
ISSN:1662-0631
1662-0631
DOI:10.1159/000529671