Research progress on immune aging and its mechanisms affecting geriatric diseases

Research progress on immune aging and its mechanisms affecting geriatric diseases

Immunosenescence, also known as immune aging, refers to the degeneration, compensation, and reconstruction of the immune system with aging. Immune aging is an important factor in the increased susceptibility of the elderly to infectious diseases, malignant tumors, and a variety of chronic diseases a...

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Veröffentlicht in:Aging medicine 2019-12, Vol.2 (4), p.216-222
Hauptverfasser: Yu, Yanping, Zheng, Songbai
Format: Artikel
Sprache:eng
Schlagworte:
Age
Aging
Antigens
Blood
Bone marrow
Cytokines
Dendritic cells
Human body
immune aging
immune cells
immune organs
Immunoglobulins
immunosenescence
Infections
Lymphatic system
Lymphocytes
Metastasis
Pathogens
Review
Spleen
Tumor necrosis factor-TNF
Tumors
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Beschreibung
Zusammenfassung:Immunosenescence, also known as immune aging, refers to the degeneration, compensation, and reconstruction of the immune system with aging. Immune aging is an important factor in the increased susceptibility of the elderly to infectious diseases, malignant tumors, and a variety of chronic diseases and has long been a hotspot in geriatrics and immunology research. In this paper, the characteristics and progression of immune aging are briefly reviewed for clinicians' reference.
ISSN:2475-0360
2475-0360
DOI:10.1002/agm2.12089