Sistemas transportadores de drogas Drug delivery systems

Drug delivery system controls the distribution of drugs for optimal therapeutic efficacy. The complex of higly active drugs with macromolecular carriers seems to offer a promising way to optimize their delivery. Dendrimers can be used as drug delivery system and this paper addresses the effectivenes...

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Veröffentlicht in:Química nova 1998-07, Vol.21 (4), p.470-476
Hauptverfasser: Maria Luiza C. Montanari, Carlos Alberto Montanari, Dorila Piló-Veloso, A. E. Beezer, J. C. Mitchell
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Sprache:eng
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Zusammenfassung:Drug delivery system controls the distribution of drugs for optimal therapeutic efficacy. The complex of higly active drugs with macromolecular carriers seems to offer a promising way to optimize their delivery. Dendrimers can be used as drug delivery system and this paper addresses the effectivenes of the approach. The host-guest system improves the solubility of hydrazides and mesoionic 1,3,4-thiadiazolium-2-aminide compounds.
ISSN:0100-4042
1678-7064
DOI:10.1590/S0100-40421998000400017