Clinical features and treatment strategies of febrile urinary tract infection caused by extended-spectrum beta-lactamase–producing Enterobacteriaceae in children: a multicenter retrospective observational study in Japan

•This is the first multicenter study on extended-spectrum beta-lactamase–related febrile urinary tract infections in Japanese children.•Risk factors include previous history of febrile urinary tract infections and recent antibiotic use.•Most patients who started on discordant antibiotics experienced clinical improvement. The incidence of infections caused by extended-spectrum beta-lactamase (ESBL)–producing bacteria has increased. This study aimed to clarify the risk factors and treatment strategies for febrile urinary tract infection (fUTI) caused by ESBL-producing bacteria in Japanese children. A retrospective observational study was conducted in 21 hospitals among children aged