Dietary phenotype and advanced glycation end-products predict WTC-obstructive airways disease: a longitudinal observational study

Diet is a modifier of metabolic syndrome which in turn is associated with World Trade Center obstructive airways disease (WTC-OAD). We have designed this study to (1) assess the dietary phenotype (food types, physical activity, and dietary habits) of the Fire Department of New York (FDNY) WTC-Health...

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Veröffentlicht in:	Respiratory research 2021-01, Vol.22 (1), p.19-12, Article 19
Hauptverfasser:	Lam, Rachel, Kwon, Sophia, Riggs, Jessica, Sunseri, Maria, Crowley, George, Schwartz, Theresa, Zeig-Owens, Rachel, Colbeth, Hilary, Halpren, Allison, Liu, Mengling, Prezant, David J, Nolan, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Advanced glycation end products Advanced glycosylation end products Age Beverages Biomarkers Blood pressure Bronchodilators Cholesterol Chronic obstructive pulmonary disease Cohort Studies Complications and side effects Development and progression Diet Eating Feeding Behavior - physiology Female Firefighters Food Food processing Glycation End Products, Advanced - administration & dosage Glycation End Products, Advanced - adverse effects Glycosylation Health aspects Humans Hyperglycemia Hypersensitivity Hypertension Longitudinal Studies Lung diseases Lung Diseases, Obstructive - chemically induced Lung Diseases, Obstructive - diagnosis Lung Diseases, Obstructive - epidemiology Male Metabolic disorders Metabolic syndrome Metabolic syndrome X Metabolism Metabolomics Methacholine Middle Aged Monitoring New York City - epidemiology Nutrient deficiency Nutrition Nutrition research Obesity Observational studies Particulate matter Phenotype Phenotypes Phenotyping Physical activity Predictive Value of Tests Questionnaires Regression analysis Regression models Risk analysis Risk factors September 11 Terrorist Attacks - trends Smoking Triglycerides Weight control
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Beschreibung
Zusammenfassung:	Diet is a modifier of metabolic syndrome which in turn is associated with World Trade Center obstructive airways disease (WTC-OAD). We have designed this study to (1) assess the dietary phenotype (food types, physical activity, and dietary habits) of the Fire Department of New York (FDNY) WTC-Health Program (WTC-HP) cohort and (2) quantify the association of dietary quality and its advanced glycation end product (AGE) content with the development of WTC-OAD. WTC-OAD, defined as developing WTC-Lung Injury (WTC-LI; FEV
ISSN:	1465-993X 1465-9921 1465-993X 1465-9921
DOI:	10.1186/s12931-020-01596-6