An elevated platelet-to-lymphocyte ratio is associated with a higher risk of intracranial atherosclerotic stenosis

An elevated platelet-to-lymphocyte ratio is associated with a higher risk of intracranial atherosclerotic stenosis

Background:Previous studies have shown that inflammation plays an important role in intracranial atherosclerotic stenosis (ICAS). The platelet-to-lymphocyte ratio (PLR) has recently emerged as a potential inflammatory biomarker. This study aimed to explore the association of the PLR with ICAS in a C...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chinese medical journal 2022-06, Vol.135 (12), p.1425-1431
Hauptverfasser: Huang, Yan-Hua, Wang, Zuo-Teng, Zhao, Bing, Ma, Ya-Hui, Ou, Ya-Nan, Hu, Hao, Hou, Xiao-He, Yu, Jin-Tai, Tan, Lan
Format: Artikel
Sprache:eng
Schlagworte:
Atherosclerosis
Automation
Biomarkers
Blood diseases
Blood platelets
Blood pressure
Cardiovascular disease
Carotid arteries
Diabetes
Drugs
Fasting
Glucose
Hypertension
Laboratories
Lipids
Lymphocytes
Magnetic resonance imaging
Medical imaging
Medical screening
Original
Stroke
Values
Variables
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background:Previous studies have shown that inflammation plays an important role in intracranial atherosclerotic stenosis (ICAS). The platelet-to-lymphocyte ratio (PLR) has recently emerged as a potential inflammatory biomarker. This study aimed to explore the association of the PLR with ICAS in a Chinese Han population.Methods:A total of 2134 participants (518 with ICAS, 1616 without ICAS) were enrolled in this study. ICAS was defined as atherosclerotic stenosis >50% or the occlusion of several main intracranial arteries. Multivariable logistic regression analyses were used to assess the association of the PLR with ICAS. Additional subgroup analyses were performed according to age (
ISSN:2542-5641
0366-6999
2542-5641
DOI:10.1097/CM9.0000000000002228