Enterovirus A71 Phenotypes Causing Hand, Foot and Mouth Disease, Vietnam

We investigated enterovirus A71-associated hand, foot and mouth disease in Vietnam and found that, after replacing subgenogroup C4 in 2013, B5 remained the leading cause of this disease. In contrast with previous observations, this switch did not result in an explosive outbreak, and B5 evolution was...

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Veröffentlicht in:	Emerging infectious diseases 2019-04, Vol.25 (4), p.788-791
Hauptverfasser:	Van, Hoang Minh Tu, Anh, Nguyen To, Hong, Nguyen Thi Thu, Nhu, Le Nguyen Truc, Nguyet, Lam Anh, Thanh, Tran Tan, Ny, Nguyen Thi Han, Hang, Vu Thi Ty, Khanh, Truong Huu, Viet, Ho Lu, Viet, Do Chau, Tuan, Ha Manh, Hung, Nguyen Thanh, Quy, Du Tuan, Ha, Do Quang, Qui, Phan Tu, Nhan, Le Nguyen Thanh, Thwaites, Guy, Chau, Nguyen Van Vinh, Thwaites, Louise, Rogier van Doorn, H, Van Tan, Le
Format:	Artikel
Sprache:	eng
Schlagworte:	and Mouth Disease Coxsackievirus infections Dispatch Enterovirus A, Human - genetics Enterovirus A71 Foot Foot and mouth disease Genetic aspects Hand Hand, Foot and Mouth Disease - epidemiology Hand, Foot and Mouth Disease - virology Humans Phenotypes Picornaviruses Vietnam Vietnam - epidemiology
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Beschreibung
Zusammenfassung:	We investigated enterovirus A71-associated hand, foot and mouth disease in Vietnam and found that, after replacing subgenogroup C4 in 2013, B5 remained the leading cause of this disease. In contrast with previous observations, this switch did not result in an explosive outbreak, and B5 evolution was driven by negative selection.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2504.181367