Neuromeningeal cryptococcosis in a patient not infected with human immunodeficiency virus and without known risk factors: A case report

We report a 24‐year‐old female patient not infected with human immunodeficiency virus (HIV) and without other risk factors of immunosuppression, presenting with neuromeningeal cryptococcosis. Cerebrospinal fluid (CSF) analysis revealed the presence of Cryptococcus neoformans. The evolution was unfavorable and the patient died even after appropriate antifungal treatment. Testing for Cryptococcus should not be limited to immunocompromised patients. The neurologic manifestations of cryptococcosis are often less typical of meningitis. The Indian ink‐staining technique should be used routinely for all CSF examinations, regardless of the patient.