Hypothalamus-Pituitary Dysfunction as an Independent Risk Factor for Postoperative Central Nervous System Infections in Patients With Sellar Region Tumors

Hypothalamus-Pituitary Dysfunction as an Independent Risk Factor for Postoperative Central Nervous System Infections in Patients With Sellar Region Tumors

The purpose of this study was to verify that hypothalamus-pituitary dysfunction is one of the risk factors for postoperative central nervous system infections (PCNSIs). We performed a retrospective analysis of all patients with sellar region lesions who underwent surgery between January 2016 and Nov...

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Veröffentlicht in:Frontiers in endocrinology (Lausanne) 2021-04, Vol.12, p.661305-661305
Hauptverfasser: Wen, Junxian, Yin, Rui, Chen, Yihao, Chang, Jianbo, Ma, Baitao, Zuo, Wei, Zhang, Xiao, Ma, Xiaojun, Feng, Ming, Wang, Renzhi, Ma, Wenbin, Wei, Junji
Format: Artikel
Sprache:eng
Schlagworte:
Adrenal Insufficiency - complications
Adult
Brain Neoplasms - surgery
central nervous system infections
Central Nervous System Infections - etiology
Cerebrospinal Fluid Leak - complications
Diabetes Insipidus - complications
endocrine
Endocrinology
Female
Humans
Hypothalamic Diseases - complications
hypothalamus-pituitary dysfunction
independent risk factor
Male
Middle Aged
Pituitary Diseases - complications
Postoperative Complications - etiology
Retrospective Studies
Risk Factors
sellar region tumors
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Zusammenfassung:The purpose of this study was to verify that hypothalamus-pituitary dysfunction is one of the risk factors for postoperative central nervous system infections (PCNSIs). We performed a retrospective analysis of all patients with sellar region lesions who underwent surgery between January 2016 and November 2019 at Peking Union Medical College Hospital. In total, 44 age- and sex-matched controls were enrolled. Univariate and multivariate analyses were performed to identify risk factors for PCNSIs. We enrolled 88 patients, 44 of whom had PCNSIs. Surgical approach (TCS) (P
ISSN:1664-2392
1664-2392
DOI:10.3389/fendo.2021.661305