Sex differences in the prognosis of patients with hypertrophic cardiomyopathy

Sex differences in the prognosis of patients with hypertrophic cardiomyopathy

We investigated sex-related differences in the prognosis of patients with hypertrophic cardiomyopathy (HCM) using the Korea National Health Insurance Service database. From 2010 to 2016, 9524 patients diagnosed with HCM and had more than 1-year follow-up period were analyzed. The primary endpoint wa...

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Veröffentlicht in:Scientific reports 2021-03, Vol.11 (1), p.4854-4854, Article 4854
Hauptverfasser: Kim, Minkwan, Kim, Bongsung, Choi, You-Jung, Lee, Hyun-Jung, Lee, Heesun, Park, Jun-Bean, Lee, Seung-Pyo, Han, Kyung-Do, Kim, Yong-Jin, Kim, Hyung-Kwan
Format: Artikel
Sprache:eng
Schlagworte:
692/4019
692/699/75/74
Cardiomyopathy
Congestive heart failure
Gender differences
Humanities and Social Sciences
multidisciplinary
Prognosis
Science
Science (multidisciplinary)
Sex differences
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Zusammenfassung:We investigated sex-related differences in the prognosis of patients with hypertrophic cardiomyopathy (HCM) using the Korea National Health Insurance Service database. From 2010 to 2016, 9524 patients diagnosed with HCM and had more than 1-year follow-up period were analyzed. The primary endpoint was the composite of cardiovascular death or new-onset heart failure (HF) admission. Propensity score-matching analysis was performed to adjust for different baseline characteristics. With a 4.4-years’ median follow-up interval (range 2.0–6.6 years) and male predominance (77.6%), women with HCM were older (52.6 ± 9.7 vs. 51.4 ± 9.1, p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-84335-1