Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population

An analysis of interleukin-10 (IL-10) gene polymorphism associative link with clinical variability in Kasakhs. 49 pts with systemic lupus erythematosus were included (48 female and I male). Promotive IL-10 gene region determined by a point variable in 627 locus was assessed with restrict fragment le...

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Veröffentlicht in:	Nauchno-prakticheskai͡a︡ revmatologii͡a 2003-08, Vol.41 (4), p.30-32
Hauptverfasser:	Omarbekova, Z E, Ivanova, R L, Guseva, I A, Myakotkin, V A
Format:	Artikel
Sprache:	eng ; rus
Schlagworte:	clinical polymorphism genetic heterogeneity il-10 systemic lupus erythematosus
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Zusammenfassung:	An analysis of interleukin-10 (IL-10) gene polymorphism associative link with clinical variability in Kasakhs. 49 pts with systemic lupus erythematosus were included (48 female and I male). Promotive IL-10 gene region determined by a point variable in 627 locus was assessed with restrict fragment length polymorphism method using restrictase Rsal. The results showed allele IL-10 gene polymorphism significance in disease risk determination, clinical variability and features of pathological process course in Kasakhs.
ISSN:	1995-4484 1995-4492
DOI:	10.14412/1995-4484-2003-1329