Adverse effects of maternal rheumatoid arthritis during pregnancy on children

[...]despite successful conception via ART, the live birth rate of transplanted embryos in women with RA was lower than that of women who were not diagnosed with RA. [...]rheumatologists and obstetricians and gynecologists should jointly guide patients with RA, standardize the use of drugs to maintain the stability of the condition, and administer ART in patients with RA before the age of 35 years, to effectively improve fertility rates. According to data from the Norwegian Birth Registry, the risk of pre-eclampsia in RA patients was 5.0%, compared with 3.4% in women overall. Tsuda et al[3] surveyed pregnant women in a Japanese hospital and showed that women with RA had higher rates of preterm birth than the general population (27.5% vs. 5.6%, P