MicroRNAs in Sepsis-Induced Acute Lung Injury: New Advances in Diagnostics and Therapeutic

In this commentary, we explored the advances made in miRNA and sepsis-induced acute lung injury (ALI) from the perspective of diagnosis and treatment. miRNAs play an important role in sepsis-induced ALI, including the regulation of inflammation, apoptosis, and oxidative stress, thereby participating...

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Veröffentlicht in:Intensive care research 2023-02, Vol.3 (2), p.150-155
Hauptverfasser: Liang, Guibin, He, Zhihui
Format: Artikel
Sprache:eng
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Zusammenfassung:In this commentary, we explored the advances made in miRNA and sepsis-induced acute lung injury (ALI) from the perspective of diagnosis and treatment. miRNAs play an important role in sepsis-induced ALI, including the regulation of inflammation, apoptosis, and oxidative stress, thereby participating in the progression of sepsis-induced ALI. miRNAs can act as therapeutic or diagnostic targets of sepsis-induced ALI. Also, the development of alternative or inhibitory drugs targeting specific miRNAs may be of great significance in treating sepsis-induced ALI and improving the prognosis of sepsis patients.
ISSN:2666-9862
2666-9862
DOI:10.1007/s44231-023-00031-w