Allgrove syndrome: reports of cases and literature review

We report a series of three mentally-retarded patients who presented with dysphagia, cough and recurrent pulmonary infection, adrenal insufficiency and alacrimia. Investigations included ultrasonography and CT scan of the abdomen, in addition to barium swallow, esophageal manometry and esophagoscopy confirming the diagnosis of achalasia. Glucocorticoid therapy was prescribed whereas alacrimia was managed by lubricants. In two of our patients dysphagia responded to dilatation while the third required cardiomyotomy.