Antimicrobial evaluation of novel substituted pyrimidinopyrazoles and pyrimidinotriazoles

Some novel substituted pyramidinopyrazoles and pyrimidinotriazoles have been synthesized by using 6-anisyl-5-cyan-2-hydrazine-3-N-methyl-3, 4-dihydropyrimidine-4-one as the starting material. Structures of these compounds have been established by IR, (1)H NMR, Mass and elemental analysis data and ha...

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Veröffentlicht in:	Journal of advanced pharmaceutical technology and research 2010-04, Vol.1 (2), p.236-244
Hauptverfasser:	Basavaraja, H S, Nagamani, J E, Kumar, M M J Vijay, Padmashali, Basavaraj
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Anti-infective agents Antimicrobial activity Antimicrobial agents Chemical properties Data processing Dihydrofolate reductase Health aspects Hydrazine NMR Nuclear magnetic resonance Original Pyramidinopyrazoles Pyrimidines Pyrimidinotriazoles Solvents Testing
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Beschreibung
Zusammenfassung:	Some novel substituted pyramidinopyrazoles and pyrimidinotriazoles have been synthesized by using 6-anisyl-5-cyan-2-hydrazine-3-N-methyl-3, 4-dihydropyrimidine-4-one as the starting material. Structures of these compounds have been established by IR, (1)H NMR, Mass and elemental analysis data and have been evaluated for their antimicrobial activity. Significant antimi.crobial activity was observed for some members of these series.
ISSN:	2231-4040 0976-2094 0976-2094
DOI:	10.4103/2231-4040.72267