A Simple Measure to Assess Hyperinflation and Air Trapping: 1-Forced Expiratory Volume in Three Second / Forced Vital Capacity

Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC) may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. To investigate the associations of 1-FEV3/FVC with the...

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Veröffentlicht in:	Balkan medical journal 2017-03, Vol.34 (2), p.113-118
Hauptverfasser:	Börekçi, Sermin, Demir, Tunçalp, Görek Dilektaşlı, Aslı, Uygun, Melahat, Yıldırım, Nurhayat
Format:	Artikel
Sprache:	eng
Schlagworte:	1-FEV3/FVC 12.95 Adult Aged Analysis and total lung capacity (r=0.47 p<0.0001). 1-FEV3/FVC was negatively correlated with forced expiratory flow25-75 (r=−0.84 p<0.0001). The upper limit of 95% confidence interval for 1-FEV3/FVC was 13.7%. 1-FEV3/FVC showed significant correlations with parameters of air trapping and hyperinflation measured by whole-body plethysmography. Importantly Cross-Sectional Studies Female Forced Expiratory Volume - physiology functional residual capacity-pleth (r=0.61 p<0.0001) Humans hyperinflation Lung - physiopathology Lung volume measurements Lung Volume Measurements - methods Male Middle Aged Original respectively. The mean 1-FEV3/FVC was 4.9% in the FEV1/FVC ≥70% group (n=644) vs. 24.1% in the FEV1/FVC <70% group (n=466). A positive correlation was found between 1-FEV3/FVC and residual volume (r=0.70 p<0.0001) Respiratory Function Tests - methods Retrospective Studies Severity of Illness Index Spirometry Spirometry - methods Statistics, Nonparametric these correlations were higher in study participants with FEV1/FVC <70% or FEV3/FVC < LLN compared to those with FEV1/FVC ≥70% or FEV3/FVC ≥ LLN Tıp Vital Capacity - physiology Weights and Measures - standards with a mean age of 52.5±15.6 years. Mean FEV3/FVC and 1-FEV3/FVC were 87.05
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Zusammenfassung:	Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC) may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. To investigate the associations of 1-FEV3/FVC with the spirometric measures and lung volumes that assess small airways dysfunction and reflects hyperinflation and air trapping. Retrospective cross-sectional study. Retrospective assessment of a total of 1110 cases who underwent body plethysmographic lung volume estimations between a time span from 2005 to 2012. Patients were assigned into two groups: firstly by FEV1/FVC (FEV1/FVC
ISSN:	2146-3123 2146-3131
DOI:	10.4274/balkanmedj.2015.0857